Jigsaw Fusion Looking for a new challenge? We’re solving a huge 7000-piece puzzle together on jigsawfusion.com. Join the game!

product - online puzzles

36Peachhshsjssolved 447 times
Solve puzzle
16Tati buys u!solved 414 times
Solve puzzle
25Christmas Slide Puzzlesolved 404 times
Solve puzzle
16red and blue 15 puzzlesolved 394 times
Solve puzzle
36TomaLand Redmeption Challengesolved 353 times
Solve puzzle
16Slide Puzzlesolved 344 times
Solve puzzle
16Discord Survivor Isle of Magicsolved 296 times
Solve puzzle
9qqweqweqsolved 276 times
Solve puzzle
16ALIF BA TAsolved 269 times
Solve puzzle
AHS redo sliding puzzle online
36AHS redosolved 256 times
Solve puzzle
2B: Life & Death online puzzle
162B: Life & Deathsolved 222 times
Solve puzzle
Heochan day online puzzle
9Heochan daysolved 203 times
Solve puzzle
Mario Party Slide online puzzle
16Mario Party Slidesolved 199 times
Solve puzzle
Final 13 HoH sliding puzzle online
9Final 13 HoHsolved 183 times
Solve puzzle
A collection of Rubik's cubes (with numbers) sliding puzzle online
9A collection of Rubik's cubes (with numbers)solved 153 times
Solve puzzle
Mewnamicat online puzzle
9Mewnamicatsolved 149 times
Solve puzzle
Moosevivor sliding puzzle online
36Moosevivorsolved 146 times
Solve puzzle
robots slide puzzle online puzzle
25robots slide puzzlesolved 142 times
Solve puzzle
Harry Potter Books online puzzle
9Harry Potter Bookssolved 138 times
Solve puzzle
Super Mario Puzzle online puzzle
100Super Mario Puzzlesolved 136 times
Solve puzzle
Harry Potter Chibi sliding puzzle online
9Harry Potter Chibisolved 120 times
Solve puzzle
Sliding Tiles logo but 4x4 (V2) sliding puzzle online
36Sliding Tiles logo but 4x4 (V2)solved 118 times
Solve puzzle
escape room online puzzle
25escape roomsolved 108 times
Solve puzzle
S4 Speedberry jammy online puzzle
16S4 Speedberry jammysolved 101 times
Solve puzzle
RARITY AND DIAXY :( online puzzle
9RARITY AND DIAXY :(solved 95 times
Solve puzzle
Ravenclaw online puzzle
16Ravenclawsolved 95 times
Solve puzzle
|♡|♡|♡|♡|: 3 sliding puzzle online
16|♡|♡|♡|♡|: 3solved 94 times
Solve puzzle
Kaguya Sama Slide online puzzle
16Kaguya Sama Slidesolved 93 times
Solve puzzle
Numbers and colors 24 puzzle 5x5 online puzzle
25Numbers and colors 24 puzzle 5x5solved 93 times
Solve puzzle
Besties (f14 slide puzzle) sliding puzzle online
16Besties (f14 slide puzzle)solved 92 times
Solve puzzle
xmas decoration online puzzle
16xmas decorationsolved 88 times
Solve puzzle
Harry potter transfiguration online puzzle
9Harry potter transfigurationsolved 86 times
Solve puzzle
Sliding for Safety! online puzzle
36Sliding for Safety!solved 82 times
Solve puzzle
Ron, Hermione, Harry, Draco online puzzle
9Ron, Hermione, Harry, Dracosolved 81 times
Solve puzzle
Symbols Revision online puzzle
16Symbols Revisionsolved 78 times
Solve puzzle
Clauunamica sliding puzzle online
9Clauunamicasolved 75 times
Solve puzzle
long i spelling online puzzle
16long i spellingsolved 63 times
Solve puzzle
Survivor-The Great War online puzzle
49Survivor-The Great Warsolved 62 times
Solve puzzle
Ravenclaw sliding puzzle online
9Ravenclawsolved 62 times
Solve puzzle
Hives sliding puzzle online
9Hivessolved 62 times
Solve puzzle
monopoly sliding puzzle online
16monopolysolved 60 times
Solve puzzle
The Boy Who Lived sliding puzzle online
16The Boy Who Livedsolved 58 times
Solve puzzle
SOLAT BERJEMAAH sliding puzzle online
16SOLAT BERJEMAAHsolved 57 times
Solve puzzle
Sweetness and coffee sliding puzzle online
49Sweetness and coffeesolved 55 times
Solve puzzle
Boss Baby online puzzle
16Boss Babysolved 55 times
Solve puzzle
F25 Immunity Challenge - Part 4 online puzzle
16F25 Immunity Challenge - Part 4solved 55 times
Solve puzzle
Challenge 2 online puzzle
36Challenge 2solved 54 times
Solve puzzle
Waiting Room sliding puzzle online
9Waiting Roomsolved 50 times
Solve puzzle

Online puzzle product

Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. Those born with progeria typically live to their mid-teens to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce children. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome (HGPS).

Signs and symptoms

Children with progeria usually develop the first symptoms during their first few months of life. The earliest symptoms may include a failure to thrive and a localized scleroderma-like skin condition. As a child ages past infancy, additional conditions become apparent usually around 18–24 months. Limited growth, full-body alopecia (hair loss), and a distinctive appearance (a small face with a shallow recessed jaw, and a pinched nose) are all characteristics of progeria. Signs and symptoms of this progressive disease tend to become more marked as the child ages.