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Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. Those born with progeria typically live to their mid-teens to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce children. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome (HGPS). Children with progeria usually develop the first symptoms during their first few months of life. The earliest symptoms may include a failure to thrive and a localized scleroderma-like skin condition. As a child ages past infancy, additional conditions become apparent usually around 18–24 months. Limited growth, full-body alopecia (hair loss), and a distinctive appearance (a small face with a shallow recessed jaw, and a pinched nose) are all characteristics of progeria. Signs and symptoms of this progressive disease tend to become more marked as the child ages.
black Sony PS4 controllers - Playstation controller and Ghost Recon game . Paris, France Solve puzzle
black Sony PS4 controllers 49 Piter 0
man riding horse statue during daytime - Inside of Victoria Memorial (This picture is taken by Amitav Hira) EDWARDS VII REX IMPERATOR. kolkat Solve puzzle
man riding horse statue during daytime 9 Lucjusz 0
people riding horse on snow-capped mountain - Vintage slide photo of cowboys. Solve puzzle
people riding horse on snow-capped mountain 64 Edmund 0
close-up photo of brown and white catles - I went to an area called "Spreewald" here in Germany. Together with two good friends I ren Solve puzzle
close-up photo of brown and white catles 64 Piter 0
gray cat standing near wall - snow cat. Plaza Midwood, Charlotte, NC, USA Solve puzzle
gray cat standing near wall 16 Adelajda 1
brown and white long coat medium dog painting - Title: Spaniel. Date: 1653. Institution:Rijksmuseum. Provider: Rijksmuseum. Providing Country: Nethe Solve puzzle
brown and white long coat medium dog painting 49 Piter 0
orange and white cat on green grass - The famous cat. Приморская улица, Хоста, Россия Solve puzzle
orange and white cat on green grass 9 Edmund 2
gray squirrel on brown tree trunk during daytime - Eurasian red squirrel (Sciurus vulgaris) (Veverka obecná). Okres Šumperk, Česko Solve puzzle
gray squirrel on brown tree trunk during daytime 49 Bernadetka 0
black cow standing on green grass - Cows at Dusk. Three Hills, Canada Solve puzzle
black cow standing on green grass 49 Ernesto 0
brown and white deer surrounded by green plants - We took a walk in Bradgate park, Leicestershire to try out a new camera. The park is an enclosed de Solve puzzle
brown and white deer surrounded by green plants 64 Bernadetka 0
walk before it snows - walk before it snows .................. Solve puzzle
walk before it snows 16 ели 3
white horse in water during daytime - Dog diving for toy. Credit: @DogFlirt (Photo side of FightMoreFilms). Solve puzzle
white horse in water during daytime 64 Zenek 0
two women on the window - maybe i love too much or maybe I show too little. Kraków, Poland Solve puzzle
two women on the window 49 Ernesto 0
reindeer pulling sled - Ivalo, Inari, Finland Solve puzzle
reindeer pulling sled 16 Max 2
silhouette of people riding on camels - Hiking At Sundown. sahara desert tour, Merzouga, Morocco Solve puzzle
silhouette of people riding on camels 25 Klementyna 0
woman wearing black long-sleeved shirt - Happy to be me, as I am, loving life. . Solve puzzle
woman wearing black long-sleeved shirt 16 Gracek 0
brown squirrel eating nuts - We were enjoying a cup off coffee early one morning when this little guy jumped up on the back porch Solve puzzle
brown squirrel eating nuts 25 Marianda 0
black cow eating green grass during daytime - Bison grazing - Gaur (Indian Bison). Ooty, Tamil Nadu, India Solve puzzle
black cow eating green grass during daytime 64 Filomena 0
gray monkey in bokeh photography - I shot this in Monkey Forest Bali, Indonesia. I saw the monkey just sat and give it a good shoot, th Solve puzzle
gray monkey in bokeh photography 49 Rumburak 0
brown and white goat - Finca Altozano, Valle de guadalupe, Mexico Solve puzzle
brown and white goat 64 Ernesto 0
people on river surrounded by green trees during daytime - Title: Latona and the Lycian Peasants. Institution:Rijksmuseum. Provider: Rijksmuseum. Providing Cou Solve puzzle
people on river surrounded by green trees during daytime 49 Max 1
black horse statue on brown building - Statue of Lady Godiva on horseback. Coventry, England, UK Solve puzzle
black horse statue on brown building 64 Dorothy 0
chamonix ................. - chamonix .............................................. Solve puzzle
chamonix ................. 25 ели 2
wildlife photography of a moose - Beautiful reindeer in Lapland. Lapland, Finland Solve puzzle
wildlife photography of a moose 49 Anastazy 0
brown elephant on green grass field during daytime - Moose, Grand Teton nat. park. Solve puzzle
brown elephant on green grass field during daytime 16 Francislava 0
brown horse on green grass field during daytime - Spring, horse in the pasture. Burscheid, Germany Solve puzzle
brown horse on green grass field during daytime 49 Gracek 0
white and brown cat sitting on blue wooden fence - Shenzhen, Guangdong Province, China Solve puzzle
white and brown cat sitting on blue wooden fence 16 Marianda 0
brown boxer dog - Best friends portraits, dogs. Solve puzzle
brown boxer dog 16 Ernesto 0
white cat sleeps under white comforter - On a very cold, gloomy weekend, after receiving some distressing news… this face. Solve puzzle
white cat sleeps under white comforter 64 Karmelia 0
brown reindeer - Richmond park deers. Santa has forgotten. Richmond Park, Richmond, United Kingdom Solve puzzle
brown reindeer 16 Ernesto 0
brown lioness sleeping under the car - A lioness resting under a safari car to escape the sun. Tanzania Solve puzzle
brown lioness sleeping under the car 49 Edmund 0
toddler sitting on black sled near rocking toy - Getting together — attracted by Love. Salzburgerstraße 263, 5084, Austria, Salzburg-Umgebung Solve puzzle
toddler sitting on black sled near rocking toy 16 Marianda 0
herd of cow on green grass field during daytime - Vacas pastando en un campo de Puerto Octay. Puerto Octay, Chile Solve puzzle
herd of cow on green grass field during daytime 64 Filomena 0
gray duck and white ram on green grass - Saksun, Faroe Islands Solve puzzle
gray duck and white ram on green grass 9 Filomena 0
woman in black long sleeve shirt - woman in black long sleeve shirt sitting on brown tree branch. . Solve puzzle
woman in black long sleeve shirt 25 Sergiusz 0
on holidays - on holidays ................................... Solve puzzle
on holidays 36 ели 1
Waiting for Christmas - Waiting for Christmas............................... Solve puzzle
Waiting for Christmas 25 ели 1
woman in white tank top carrying brown bear plush toy - Girl holding puppy while smiling. . Murfreesboro, TN, USA Solve puzzle
woman in white tank top carrying brown bear plush toy 9 Rumburak 1
gray koala on tree - Phillip Island, Australia Solve puzzle
gray koala on tree 64 Karmelia 0
santa claus with red background - Old senior man with grey hair and long beard wearing santa claus costume holding glasses afraid and Solve puzzle
santa claus with red background 16 Edmund 1
selective focus photography of brown moose - selective focus photography of brown moose surrounded by trees. . US National Park Road, Grand Lake, Solve puzzle
selective focus photography of brown moose 49 Klementyna 0
wild beauty - wild beauty ........................... Solve puzzle
wild beauty 25 ели 3