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Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. Those born with progeria typically live to their mid-teens to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce children. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome (HGPS). Children with progeria usually develop the first symptoms during their first few months of life. The earliest symptoms may include a failure to thrive and a localized scleroderma-like skin condition. As a child ages past infancy, additional conditions become apparent usually around 18–24 months. Limited growth, full-body alopecia (hair loss), and a distinctive appearance (a small face with a shallow recessed jaw, and a pinched nose) are all characteristics of progeria. Signs and symptoms of this progressive disease tend to become more marked as the child ages.
six round chocolates - Macarons in Chocolate . Solve puzzle
six round chocolates 36 Rumburak 0
Valencia, Venezuela - person holding two baseballs. Estadio José Bernardo Pérez, Valencia, Venezuela Solve puzzle
Valencia, Venezuela 9 Piter 0
Cave, underground - brown and black cave painting. Nickelsville, VA, USA Solve puzzle
Cave, underground 64 Anastazy 0
man sitting cliff rock - Blyde River Canyon, Mpumulanga. Second largest canyon in Africa. Blyde River Canyon, Mpumulanga, Sou Solve puzzle
man sitting cliff rock 64 Adelajda 0
woman holding flowers - Woman with a bouquet in the meadow. Pleiku, Vietnam Solve puzzle
woman holding flowers 36 Dorothy 0
Blue Pacific. - brown and green mountain beside body of water during daytime. Big Sur, CA, USA Solve puzzle
Blue Pacific. 25 Dorothy 0
After meal - selective focus photo of gray cat sitting on green grass. Solve puzzle
After meal 16 Francislava 0
Series taken at Stainburn Rocks in North Yorkshire. - man in red plaid top standing on hilltop during daytime. Stainburn, United Kingdom Solve puzzle
Series taken at Stainburn Rocks in North Yorkshire. 16 Zenek 0
Hiking in Gran Canaria - brown trees under cloudy sky during daytime. Gran Canaria, Spanien Solve puzzle
Hiking in Gran Canaria 49 Piter 0
Nala being a perfect model - black and white short coated dog on brown grass field during daytime. Solve puzzle
Nala being a perfect model 25 Max 2
Autumn landscape - Autumn landscape................................... Solve puzzle
Autumn landscape 36 ели 1
stream in the mountains - landscape - a stream in the mountains Solve puzzle
stream in the mountains 25 ели 1
in early autumn - in the beginning of autumn ............................... Solve puzzle
in early autumn 36 ели 1
orange pumpkins under white sky at daytime - When the lighting is right, and you have your camera with you, you take some pretty pictures of your Solve puzzle
orange pumpkins under white sky at daytime 49 Bernadetka 0
landscape - lakes - landscape - lakes .................................... Solve puzzle
landscape - lakes 25 ели 1
in the mountains - in the mountains..................................... Solve puzzle
in the mountains 36 ели 1
Brombeerstrauch - red and black grapes. Solve puzzle
Brombeerstrauch 16 Marianda 0
landscape of the Rhodopes - landscape of the Rhodopes ............................. Solve puzzle
landscape of the Rhodopes 36 ели 1
The Rocks of Belogradchik - The Rocks of Belogradchik......................... Solve puzzle
The Rocks of Belogradchik 49 ели 1
crocuses in the rhyme - crocuses in the rhyme ............................ Solve puzzle
crocuses in the rhyme 36 ели 1
Autumn landscape - autumn landscape in the mountains Solve puzzle
Autumn landscape 64 ели 1
brown squirrel - I love Squirrels, I think they're such fascinating creatures. The ones in Canada are quite a bi Solve puzzle
brown squirrel 16 Felicjusz 0
hedgehog in leaves - 3o pieces - a puzzle for children Solve puzzle
hedgehog in leaves 36 aaa 0
Child in tutu. - toddler girl wearing teal and white polka-dot long-sleeved shirt and white tutu skirt outfit walking Solve puzzle
Child in tutu. 9 Francislava 0
Magic mirror - forest and body of water during night. Tiszafüred, Hungary Solve puzzle
Magic mirror 36 Filomena 4
Climbing up from ocean - closeup photo of person's hand. Solve puzzle
Climbing up from ocean 25 Karmelia 0
bridge over the waterfall - bridge over the waterfall ................................ Solve puzzle
bridge over the waterfall 36 ели 2
waterfall ...................... - waterfall .............................................. Solve puzzle
waterfall ...................... 25 ели 3
wide meadow area - wide meadow area .......................... Solve puzzle
wide meadow area 36 ели 1
green-leafed tree - Tuluk River & Rocks. Tuluk River Solve puzzle
green-leafed tree 25 Klementyna 0
Tuscan landscape ............... - Tuscan landscape ............................... Solve puzzle
Tuscan landscape ............... 36 ели 2
The three in Etosha No. 1, Namibia - three brown giraffe on seashore during daytime. Etosha, Namibia Solve puzzle
The three in Etosha No. 1, Namibia 49 Ernesto 0
wood in the forest - wood in the forest .............................. Solve puzzle
wood in the forest 25 ели 1
river and strandja mountain - river and strandja mountain ..................... Solve puzzle
river and strandja mountain 25 ели 0
Strandzha mountain - Strandzha Mountain ............................ Solve puzzle
Strandzha mountain 36 ели 3
Farming in Frederick - man standing in foggy area. Frederick Solve puzzle
Farming in Frederick 9 Bernadetka 0
last pumpkin of the year - Jack-O'-Lantern decor near green leaf plant. Solve puzzle
last pumpkin of the year 49 Rumburak 0
mountain ranges - Dark clouds over Peak District, UK. Solve puzzle
mountain ranges 49 Felicjusz 0
Pumpkin Picking - photography of pumpkins on ground at daytime. Cider Hill Farm, Amesbury, United States Solve puzzle
Pumpkin Picking 16 Bernadetka 0
pumpkin lot - Fall in Ontario. Ontario, Canada Solve puzzle
pumpkin lot 64 Max 0
tall trees on hills - Wayanad Monsoon, Shotoniphone. Solve puzzle
tall trees on hills 36 Karmelia 0
landscape ................................. - landscape ................................................. .... Solve puzzle
landscape ................................. 25 ели 1