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Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. Those born with progeria typically live to their mid-teens to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce children. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome (HGPS). Children with progeria usually develop the first symptoms during their first few months of life. The earliest symptoms may include a failure to thrive and a localized scleroderma-like skin condition. As a child ages past infancy, additional conditions become apparent usually around 18–24 months. Limited growth, full-body alopecia (hair loss), and a distinctive appearance (a small face with a shallow recessed jaw, and a pinched nose) are all characteristics of progeria. Signs and symptoms of this progressive disease tend to become more marked as the child ages.
boy in blue and black backpack standing near body of water Solve puzzle
boy in blue and black backpack standing near body of water 100 Thomas Park 0
brown animal on brown grass field during daytime Solve puzzle
brown animal on brown grass field during daytime 16 Dylan Leagh 0
white and brown concrete houses Solve puzzle
white and brown concrete houses 25 Gabriella Clare Marino 0
green trees near river under blue sky during daytime Solve puzzle
green trees near river under blue sky during daytime 100 Alex Grodkiewicz 0
brown deer on brown grass during daytime Solve puzzle
brown deer on brown grass during daytime 36 Ahmad Omari 0
red and black bicycle in the woods Solve puzzle
red and black bicycle in the woods 64 Ron Westerwell 0
man in green jacket walking on green grass field Solve puzzle
man in green jacket walking on green grass field 16 Abed Ismail 0
brown brick wall near green grass field and mountain Solve puzzle
brown brick wall near green grass field and mountain 49 Juvnsky Anton Maksimov 0
woman in blue jacket and black pants Solve puzzle
woman in blue jacket and black pants 16 Nathaniel Ramirez 0
football players in red jersey shirt and pants Solve puzzle
football players in red jersey shirt and pants 81 Ryan Reinoso 0
white metal fence near green grass field during daytime Solve puzzle
white metal fence near green grass field during daytime 25 Nick Fewings 0
2 boys playing on green field Solve puzzle
2 boys playing on green field 64 Rahadiansyah 0
people in green and black shirts standing on brown field Solve puzzle
people in green and black shirts standing on brown field 16 Omar Tursić 0
black and white short coated dog standing on brown rock Solve puzzle
black and white short coated dog standing on brown rock 16 Nathalie Ehrnleitner 0
brown short coated dog on gray asphalt road during daytime Solve puzzle
brown short coated dog on gray asphalt road during daytime 16 Nathalie Ehrnleitner 0
blue and white wooden house on green grass field Solve puzzle
blue and white wooden house on green grass field 49 Maggie Yap 0
green grass field near mountain under cloudy sky Solve puzzle
green grass field near mountain under cloudy sky 81 Tierras Altas Escocia 0
man in red shirt and black pants playing soccer Solve puzzle
man in red shirt and black pants playing soccer 36 Omar Ram 0
man in brown shirt standing on green grass field Solve puzzle
man in brown shirt standing on green grass field 36 Samuel Heuberger Reichert 0
black bicycle on gray concrete bridge during daytime Solve puzzle
black bicycle on gray concrete bridge during daytime 81 Miguel Castellanos 0
woman in black jacket and blue denim jeans Solve puzzle
woman in black jacket and blue denim jeans 100 Kali Elias 0
brown animal on brown rock Solve puzzle
brown animal on brown rock 9 Jéan Béller 0
man in brown and black camouflage jacket Solve puzzle
man in brown and black camouflage jacket 16 Chase Baker 0
white boat on river near trees during daytime Solve puzzle
white boat on river near trees during daytime 49 Dana Marin (Amsterdamian) 0
cheetah walking on brown grass field during daytime Solve puzzle
cheetah walking on brown grass field during daytime 64 Gaurav Chhaperwal 0
white and brown short coated dog on brown soil Solve puzzle
white and brown short coated dog on brown soil 100 Mitchell Orr 0
green trees under blue sky during daytime Solve puzzle
green trees under blue sky during daytime 64 Aldeen Li 0
gray and white bird on brown grass Solve puzzle
gray and white bird on brown grass 9 Trac Vu 2
green grass field on rocky mountain under blue sky Solve puzzle
green grass field on rocky mountain under blue sky 16 Juvnsky Anton Maksimov 0
gray and white bird on green grass during daytime Solve puzzle
gray and white bird on green grass during daytime 49 Abed Ismail 0
brown animal on brown grass field during daytime Solve puzzle
brown animal on brown grass field during daytime 81 Dylan Leagh 0
brown pathway between brown trees during daytime Solve puzzle
brown pathway between brown trees during daytime 49 Sajad Nori 0
white and brown wooden houses on green grass field Solve puzzle
white and brown wooden houses on green grass field 36 Jonas from Berlin 0
man in black jacket and blue denim jeans Solve puzzle
man in black jacket and blue denim jeans 16 Polina Kuzovkova 0
green and brown grass field under white clouds Solve puzzle
green and brown grass field under white clouds 100 Pete Crockett 0
man in white t-shirt standing on green grass field Solve puzzle
man in white t-shirt standing on green grass field 100 William Freitas 0
man in blue crew neck t-shirt standing beside man Solve puzzle
man in blue crew neck t-shirt standing beside man 100 Chase Baker 0
brown deer on brown dried leaves Solve puzzle
brown deer on brown dried leaves 64 Joe Dudeck 0
green grass field under blue sky during daytime Solve puzzle
green grass field under blue sky during daytime 49 Juvnsky Anton Maksimov 0
brown and white concrete building during daytime Solve puzzle
brown and white concrete building during daytime 81 Austin Goode 0
green and brown mountain beside lake under white cloudy sky Solve puzzle
green and brown mountain beside lake under white cloudy sky 9 Tierras Altas Escocia 0
gray concrete road near green mountains during daytime Solve puzzle
gray concrete road near green mountains during daytime 100 Aleeza Jilani 0